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Argireline

Acetyl Hexapeptide-3
Also known as: Acetyl Hexapeptide-3 · Acetyl Hexapeptide-8
Anti-agingPeptides

A topical peptide that mimics Botox by relaxing expression lines.

Skin types
All types
Pore-clogging
Non-comedogenic
Use when
Evening
Concentration
2–10%
What it does

Argireline (acetyl hexapeptide-3) is a synthetic peptide that inhibits the neurotransmitter release responsible for muscle contractions, which create expression lines over time. It works on a similar but much milder mechanism to botulinum toxin, reducing the depth of dynamic wrinkles around the eyes and forehead. Results are subtle and require consistent long-term use.

Benefits
  • Reduces the depth of expression lines around the eyes and forehead
  • Non-invasive alternative to Botox-type treatments
  • Lightweight and compatible with most routines
  • Works well in combination with other anti-aging peptides
How to layer
🌙 Evening routine
Cleanser
Toner
Serum
Moisturiser
Face Oil
After cleansing, before moisturiser
Good for
All skinNormal skinDry skinCombination skinSensitive skin
Heads up
  • Effects are subtle compared to injectable treatments
  • Requires consistent daily use to maintain results
  • Limited evidence compared to more established actives like retinol
How to use

Apply morning and/or evening as part of a serum. Can be used daily. Layer under moisturiser. Most effective when applied consistently to expression-prone areas.

Typical concentration: 2–10%