Argireline
Acetyl Hexapeptide-3
Also known as: Acetyl Hexapeptide-3 · Acetyl Hexapeptide-8
Anti-agingPeptides
“A topical peptide that mimics Botox by relaxing expression lines.”
What it does
Argireline (acetyl hexapeptide-3) is a synthetic peptide that inhibits the neurotransmitter release responsible for muscle contractions, which create expression lines over time. It works on a similar but much milder mechanism to botulinum toxin, reducing the depth of dynamic wrinkles around the eyes and forehead. Results are subtle and require consistent long-term use.
Benefits
- Reduces the depth of expression lines around the eyes and forehead
- Non-invasive alternative to Botox-type treatments
- Lightweight and compatible with most routines
- Works well in combination with other anti-aging peptides
How to layer
🌙 Evening routine
Cleanser
Toner
Serum
Moisturiser
Face Oil
After cleansing, before moisturiser
Good for
All skinNormal skinDry skinCombination skinSensitive skin
Works well with
Heads up
- ⚠Effects are subtle compared to injectable treatments
- ⚠Requires consistent daily use to maintain results
- ⚠Limited evidence compared to more established actives like retinol
How to use
Apply morning and/or evening as part of a serum. Can be used daily. Layer under moisturiser. Most effective when applied consistently to expression-prone areas.
Typical concentration: 2–10%